@@ -36,7 +36,7 @@ For Thal vs HD comparison intra population (HSC or MPP - n = 2) we used the simp
We performed Over Representation Analyses (ORA) and Gene Set Enrichment Analyses (GSEA) using R/Bioconductor package [clusterProfiler](https://bioconductor.org/packages/release/bioc/html/clusterProfiler.html)(v.3.8.1). Pre-ranked gene list according to log2FC was used to perform Gene Set Enrichment Analysis (GSEA). Terms with adjusted p-value (Benjiamini-Hochberg correction) less than 0.05 were considered significantly enriched.
7. Supplementary analysis: Music deconvolution analysis
7. Supplementary analysis
We also applied Music to perform BulkRNAseq deconvolution according to celltype specific transcriptomic profiles obtained from scRNAseq dataset (Tusi et al 2021).
