#### Interpretation of T cell states using reference atlas ####
To better characterize the composition of identified CAR-Ts, we adopted **ProjecTILs**, which is a computational method to project a single-cell dataset into a reference atlas to compare them without altering the structure of the reference one. Briefly, CAR-Ts from individual samples were independently mapped on the reference mouse TILs’ atlas; cluster composition was then assessed throughout treatment groups (i.e., Empty, IFN, oIL2, and IFN+oIL2).

- ProjectTILS_CART.R: script for the analysis of ProjectTILs on different conditions.

![Full_WPRE_CART_TILs](./Full_WPRE_CART_TILs.png)
<img src="./Full_WPRE_CART_TILs_barplot.png" alt="Full_WPRE_CART_TILs_barplot" width="300">