Amodio G, Giacomini G, Boeri L, et al. **T cell exhaustion and senescence signatures characterize and differentiate infertile men**
Amodio G, Giacomini G, Boeri L, et al. **Specific types of male infertility are correlated with T cell exhaustion or senescence signaturesn**
### Single-Cell RNA Sequencing Analysis ###
**scRNAseq** (from 10X Genomics) analysis of CD3+ T cells purified from the peripheral blood of men diagnosed with oligo-astheno-teratozoospermia (OAT, n=4), idiopathic non-obstructive azoospermia (iNOA, n=6), and a control group (FER, n=5).
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@@ -28,14 +28,6 @@ scRNAseq analysis was performed using a standard [Seurat](https://satijalab.org/
### Directories and Files ###
- sampleSheet.csv: names of samples and corresponding conditions
-**Script**: R scripts used for the analyses
-`1_PreProcessing_Data.R`: Preprocessing, cell filtering and Full object creation
-`2_Infertility_scRNAseq_analysis.R`:
-`3_SubsetAnalysis_Annotations.R`: subset analyses of T cells and cluster manual annotation
