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Vavassori_LNP2022
Vavassori_LNP2022_RNAseq_electro
Commits
bf0bc939
Commit
bf0bc939
authored
Oct 17, 2022
by
Stefano Beretta
Browse files
Added paper data.
parent
22e95c97
Changes
26
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paper_data/AAV6_D4-RNP_D4-enr-h.all.v7.2.symbols-neg.txt
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bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 39/242 185/3554 4.68411484748802e-11 2.34205742374401e-09 1.82433946691639e-09 ZC3H12A/PPP1R15A/GEM/GADD45B/MYC/CD44/INHBA/KLF10/SQSTM1/PDE4B/IL15RA/KLF6/ETS2/TSC22D1/CCNL1/SERPINB2/DENND5A/IFIT2/NFAT5/PTGS2/CCND1/DUSP4/TUBB2A/CXCL11/KDM6B/SMAD3/CD83/NAMPT/PHLDA1/SOD2/MXD1/JUN/IRF1/FOSB/IER3/TNC/SOCS3/RIPK2/SPHK1 39
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 32/242 192/3554 1.08698210659666e-06 2.71745526649165e-05 2.1167546286356e-05 SLAMF7/APOL6/GBP4/RSAD2/WARS1/PDE4B/IL15RA/CSF2RB/IL15/IFIT2/IFIT3/PTGS2/CXCL11/EPSTI1/TRIM25/JAK2/STAT1/PIM1/NAMPT/SOD2/ZNFX1/IRF1/PELI1/UPP1/PARP14/CD274/NLRC5/SOCS3/RIPK2/IRF9/SPPL2A/ARID5B 32
HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING 15/242 72/3554 7.00975873040559e-05 0.00108116783731711 0.000842172841699647 IL1R1/CD44/IL15RA/CSF2RB/CXCL11/IL1R2/STAT1/HMOX1/PIM1/JUN/IRF1/IL18R1/LEPR/SOCS3/IRF9 15
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 27/242 184/3554 8.64934269853692e-05 0.00108116783731711 0.000842172841699647 NFKBIZ/GBP4/IL1RL1/GADD45B/MYC/CD44/HIPK2/AHNAK/PLEC/KLF6/AHR/DENND5A/GABARAPL1/IL1R2/GATA1/CD83/PIM1/PLIN2/PHLDA1/MXD1/PRNP/BCL2/IL18R1/PLAGL1/TNFRSF8/CDCP1/LRRC8C 27
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 23/242 153/3554 0.000205697742321378 0.00205697742321378 0.00160227715071389 IL1R1/MYC/INHBA/CXCL8/PDE4B/IL15RA/KLF6/IL15/AHR/AQP9/RGS1/P2RX7/CXCL11/TPBG/PTAFR/NAMPT/SLC7A1/MXD1/IRF1/IL18R1/RIPK2/CCR7/SPHK1 23
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 20/242 129/3554 0.000356118458708471 0.00296765382257059 0.00231164613547604 GEM/GADD45B/VIM/CD44/INHBA/CXCL8/THBS1/FERMT2/IL15/MGP/LAMC2/JUN/MYLK/SERPINE2/CD59/TNC/GLIPR1/ECM2/ITGA2/NID2 20
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 20/242 146/3554 0.00178224576999965 0.0127303269285689 0.00991625466014841 CTH/ANXA1/GADD45B/CD44/LMNA/PDCD4/SQSTM1/LGALS3/CAV1/BMF/CCND1/FEZ1/HMOX1/SOD2/CLU/JUN/IRF1/DDIT3/IER3/SLC20A1 20
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 21/242 171/3554 0.00529843489095853 0.029791124430204 0.0232057179772115 STC2/PPP1R15A/KLF6/NR3C1/KLHL24/CAV1/TPBG/IDS/MXI1/HMOX1/PIM1/PLIN2/JUN/EXT1/ANXA2/DDIT3/IER3/BCL2/NEDD4L/LARGE1/AMPD3 21
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 14/242 97/3554 0.00536240239743671 0.029791124430204 0.0232057179772115 GBP4/RSAD2/WARS1/IL15/NUB1/IFIT2/IFIT3/CXCL11/EPSTI1/TRIM25/IRF1/PARP14/RIPK2/IRF9 14
paper_data/AAV6_D4-RNP_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 95/650 197/3554 3.55937958004268e-23 1.77968979002134e-21 1.53615329243947e-21 IDH2/UQCRC2/ECHS1/BAX/LDHA/MAOB/IDH3G/SLC25A4/SLC25A5/ECH1/ETFB/ATP5MC3/UQCRC1/ATP5F1A/GPI/LDHB/NDUFS7/MDH1/VDAC3/ATP5MC1/UQCRQ/ACAA1/ATP5MF/NDUFB2/SLC25A11/NDUFA3/PHYH/COX6B1/MRPL11/NDUFS6/COX8A/UQCR10/MDH2/NDUFB1/NDUFB6/ATP5ME/ATP5F1C/NDUFA2/HADHB/COX4I1/NDUFAB1/COX7C/NDUFC1/IDH3B/UQCRH/PDHA1/HSD17B10/COX5B/NDUFB8/COX5A/NDUFV1/ATP5PB/UQCRB/FH/NDUFS3/POLR2F/COX7B/VDAC1/ATP5F1B/ATP5PF/NDUFA1/MRPS15/NDUFS8/CYC1/ATP5MG/ETFA/NDUFB7/SDHB/NDUFA4/NDUFB3/ACAA2/NDUFB4/UQCRFS1/NDUFA8/ATP5PD/MRPL35/SDHC/COX7A2/NDUFA9/ATP5PO/SUCLG1/COX6A1/CYB5A/COX17/TOMM22/COX6C/BDH2/NDUFC2/ATP5F1E/TIMM10/NDUFS4/TIMM8B/ATP6V1D/PHB2/PRDX3 95
HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM 47/650 131/3554 8.61319803989667e-07 2.15329950997417e-05 1.85863747176718e-05 ECHS1/ACAT2/G0S2/MAOA/LDHA/ECI2/IDH3G/ECH1/AUH/PRDX6/LGALS1/SUCLG2/MDH1/ACAA1/GCDH/CBR3/HADH/MDH2/UROS/HADHB/IDH3B/PDHA1/HSD17B10/BCKDHB/FH/NTHL1/PCBD1/REEP6/SMS/H2AZ1/ALDH3A2/ACAA2/GRHPR/BLVRA/SDHC/IL4I1/ENO2/UROD/SUCLG1/HSD17B7/HSD17B4/HIBCH/ACOT8/DHCR24/CRYZ/HSDL2/ACADS 47
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 53/650 171/3554 2.6020844679461e-05 0.000433680744657683 0.000374334958546631 P4HA2/ALDOC/BNIP3L/TMEM45A/PLAC8/PGK1/TPI1/GAPDH/PPFIA4/GLRX/CCNG2/PGM1/LDHA/GBE1/KDELR3/GYS1/FAM162A/AK4/GPI/MT1E/ENO1/GALK1/SLC37A4/ILVBL/DPYSL4/CASP6/EFNA3/SDC2/AKAP12/PDK1/CAVIN1/SCARB1/ANKZF1/SLC2A3/XPNPEP1/UGP2/GRHPR/S100A4/PGM2/ENO2/SLC2A1/P4HA1/MT2A/GAA/CDKN1B/STC1/RRAGD/CCN1/HK1/TGM2/RBPJ/NFIL3/WSB1 53
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 53/650 174/3554 4.45025166235006e-05 0.000556281457793757 0.000480158731990401 P4HA2/PGK1/TPI1/PPFIA4/GLRX/PLOD2/LDHA/ALDH7A1/KDELR3/SLC16A3/GMPPB/BIK/GYS1/FAM162A/AK4/FUT8/PGAM1/ENO1/MPI/SLC25A10/GALK1/SLC37A4/MDH1/DPYSL4/SPAG4/CASP6/GALE/EFNA3/SDC2/MDH2/IL13RA1/ANKZF1/PSMC4/TALDO1/PLOD1/PPIA/UGP2/SDC1/NASP/KIF20A/SDHC/PGM2/ENO2/GMPPA/CYB5A/P4HA1/STMN1/STC1/RRAGD/SOD1/TSTA3/PKM/SLC25A13 53
HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1 57/650 200/3554 0.000180049969406494 0.00180049969406494 0.00155411552540342 PGK1/CDK2/LDHA/CDC45/SRSF7/MRPL23/PSMB3/RUVBL2/TYMS/HNRNPD/VDAC3/NHP2/PSMD8/NME1/SNRPD2/AP3S1/RPS5/RANBP1/PRPF31/IMPDH2/NDUFAB1/SNRPA1/HSPE1/HNRNPA1/PSMC4/COX5A/LSM7/PPIA/PCNA/TUFM/PA2G4/VDAC1/SNRPG/PSMB2/CYC1/HNRNPA3/HNRNPA2B1/H2AZ1/LSM2/SNRPA/FBL/RPS3/PHB/RFC4/RPL18/DUT/NPM1/TXNL4A/HPRT1/SNRPB2/EXOSC7/RPL6/PHB2/PRDX3/CCT7/RPL34/SSBP1 57
HALLMARK_DNA_REPAIR HALLMARK_DNA_REPAIR 43/650 145/3554 0.000452501136765981 0.00377084280638317 0.00325483273814127 NME4/RFC5/ADA/GSDME/MPG/POLR2I/GUK1/RFC2/TYMS/NELFE/ZWINT/SDCBP/POLB/NME1/POLR2H/ZNRD1/BCAP31/IMPDH2/USP11/NME3/RPA3/POLR2G/POLR2J/PCNA/EDF1/POLR2F/NUDT21/MRPL40/APRT/NT5C/RFC4/GTF2H5/POLR2E/COX17/DUT/SNAPC5/POLD4/PDE6G/DAD1/HPRT1/RBX1/LIG1/POLA2 43
HALLMARK_ADIPOGENESIS HALLMARK_ADIPOGENESIS 46/650 177/3554 0.00576741678064564 0.0411958341474689 0.0355585094746573 ECHS1/UCP2/CCNG2/TST/PGM1/IDH3G/CAT/GBE1/ECH1/ETFB/UQCRC1/SLC25A10/CMBL/UQCRQ/PHYH/COX8A/HADH/UQCR10/SAMM50/MDH2/EPHX2/CAVIN1/NDUFAB1/ESYT1/SCARB1/CHCHD10/TALDO1/COQ3/NDUFS3/COX7B/REEP6/CYC1/NDUFB7/SDHB/ACAA2/COQ9/CDKN2C/SDHC/ATP5PO/SUCLG1/COX6A1/HIBCH/PEMT/SOD1/PRDX3/ACADS 46
paper_data/AAV6_D4-UT_D4-enr-h.all.v7.2.symbols-neg.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_HEME_METABOLISM HALLMARK_HEME_METABOLISM 1/1 171/3508 0.0487457240592929 0.0487457240592929 NA HBD 1
paper_data/AAV6_D4-UT_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 13/16 185/3508 7.88847807458912e-15 1.73546517640961e-13 1.57769561491782e-13 PLK2/SESN1/FDXR/CDKN1A/BAX/ZMAT3/FAS/PHLDA3/KRT17/ATF3/DRAM1/PLXNB2/RNF19B 13
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 5/16 145/3508 0.00034010434926901 0.00374114784195911 0.0034010434926901 FDXR/CDKN1A/BAX/FAS/ATF3 5
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 5/16 183/3508 0.000997630806462901 0.00731595924739461 0.00665087204308601 PLK2/CDKN1A/ATF3/DRAM1/RNF19B 5
paper_data/AAV6_D4-UT_electro_D4-enr-h.all.v7.2.symbols-neg.txt
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bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 33/166 181/3464 5.56670280617925e-12 2.72768437502783e-10 2.05089050753972e-10 ZC3H12A/INHBA/CD44/MYC/GEM/GADD45B/PPP1R15A/PTGS2/SQSTM1/PDE4B/KLF10/IL15RA/SERPINB2/NAMPT/CCNL1/CD83/KLF6/TSC22D1/NFAT5/CCND1/DUSP4/SOCS3/ETS2/IER3/MXD1/PHLDA1/TUBB2A/SMAD3/SPHK1/FOSL1/SOD2/TNC/CXCL11 33
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 22/166 182/3464 3.84718931740628e-05 0.000847935055318532 0.000637545154374836 NFKBIZ/IL1RL1/CD44/MYC/GBP4/GADD45B/AHNAK/PLEC/GATA1/CD83/AHR/TNFRSF8/NOP2/KLF6/HIPK2/IL18R1/IL1R2/CDCP1/PIM1/MXD1/PHLDA1/RORA 22
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 19/166 149/3464 6.49461359246134e-05 0.000847935055318532 0.000637545154374836 IL1R1/INHBA/MYC/CXCL8/AQP9/PDE4B/IL15RA/NAMPT/RGS1/AHR/IL15/KLF6/IL18R1/P2RX7/MXD1/TPBG/SPHK1/SGMS2/CXCL11 19
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 22/166 189/3464 6.9219188189268e-05 0.000847935055318532 0.000637545154374836 SLAMF7/WARS1/GBP4/CSF2RB/RSAD2/APOL6/PTGS2/PDE4B/IL15RA/UPP1/NAMPT/IL15/JAK2/TRIM25/SOCS3/STAT1/PIM1/NLRC5/RNF31/SOD2/CXCL11/CD274 22
HALLMARK_COAGULATION HALLMARK_COAGULATION 12/166 75/3464 0.000184160472188845 0.00180477262745068 0.00135697190033886 CRIP2/ANXA1/CAPN2/MMP10/SERPINB2/THBS1/CTSO/DPP4/ITGA2/CLU/TMPRSS6/SERPINA1 12
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 14/166 118/3464 0.00129246291609754 0.00995166193686955 0.00748245258411245 INHBA/CD44/CXCL8/GEM/VIM/GADD45B/THBS1/IL15/LAMC2/MGP/FERMT2/ITGA2/CD59/TNC 14
HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING 10/166 69/3464 0.00142166599098136 0.00995166193686955 0.00748245258411245 IL1R1/CD44/CSF2RB/IL15RA/IL18R1/SOCS3/IL1R2/STAT1/PIM1/CXCL11 10
paper_data/AAV6_D4-UT_electro_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 41/407 196/3464 0.000107761346174216 0.0052803059625366 0.00465075283488723 BAX/IDH2/MAOB/UQCRC2/ECHS1/SLC25A4/LDHA/IDH3G/ECH1/SLC25A5/LDHB/ETFB/VDAC3/ATP5MC3/GPI/UQCRQ/UQCR10/NDUFB1/NDUFS6/UQCRH/NDUFB2/NDUFA2/MDH1/UQCRC1/ATP5F1A/ATP5MC1/ATP5MF/COX6B1/NDUFB6/HADHB/COX8A/NDUFA3/COX7C/ATP5PF/ATP5PO/UQCRB/NDUFA4/ATP5F1C/COX7B/ATP6V1D/MRPL11 41
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 35/407 168/3464 0.000380378274634255 0.00931926772853925 0.0082081627684234 ALDOC/P4HA2/BNIP3L/PLAC8/CCNG2/TPI1/TMEM45A/GLRX/PGK1/GAPDH/GBE1/PPFIA4/PGM1/LDHA/KDELR3/GYS1/FAM162A/CASP6/AK4/RRAGD/DPYSL4/UGP2/GPI/SDC2/SLC37A4/CDKN1B/NFIL3/ENO1/ENO2/AKAP12/CDKN1A/GPC1/ANKZF1/ILVBL/EFNA3 35
HALLMARK_MTORC1_SIGNALING HALLMARK_MTORC1_SIGNALING 38/407 197/3464 0.00105369714853295 0.0126565370648533 0.0111475407015894 FDXR/TUBA4A/TM7SF2/PLOD2/TPI1/GLRX/FADS1/PGK1/GAPDH/CCNG1/DHFR/GBE1/HSP90B1/PGM1/LDHA/LTA4H/GLA/FADS2/SLA/MLLT11/AK4/SEC11A/CALR/CORO1A/PSMD13/GPI/SLC37A4/HSPE1/TUBG1/ITGB2/ATP5MC1/NFIL3/EBP/ENO1/CDKN1A/STARD4/PSMC2/ATP6V1D 38
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 34/407 171/3464 0.0011172261691697 0.0126565370648533 0.0111475407015894 P4HA2/PLOD2/TPI1/GLRX/PGK1/PPFIA4/BIK/LDHA/KDELR3/ALDH7A1/GYS1/SLC16A3/FUT8/FAM162A/SPAG4/CASP6/AK4/GMPPB/SLC25A10/RRAGD/DPYSL4/MPI/PGAM1/UGP2/IL13RA1/SDC2/SLC37A4/MDH1/ENO1/ENO2/GPC1/ANKZF1/PLOD1/EFNA3 34
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 22/407 96/3464 0.00129148337396463 0.0126565370648533 0.0111475407015894 OAS1/MX1/BST2/PLSCR1/SELL/IFITM1/LY6E/IFITM2/IFITM3/ISG15/USP18/IFI35/LAP3/IFI44L/IFI44/IRF7/LGALS3BP/SP110/PSMB8/IFI27/DHX58/HLA-C 22
paper_data/Day12_DGE.rds
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paper_data/Day4_DGE.rds
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paper_data/RNP_AAV6_D4-AAV6_D4-enr-h.all.v7.2.symbols-neg.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 53/536 171/3464 1.21886861926747e-07 6.09434309633737e-06 5.00377643699279e-06 P4HA2/PGK1/PLOD2/ALDH7A1/LDHA/FUT8/TPI1/GYS1/KIF20A/PPFIA4/AK4/SLC25A10/GALE/MPI/SLC16A3/ENO1/SPAG4/PGAM1/GMPPB/SLC25A13/GLRX/PLOD1/FKBP4/AURKA/HMMR/TSTA3/FAM162A/MDH2/P4HA1/PGM2/ANKZF1/IL13RA1/UGP2/GALK1/CASP6/RPE/PC/TALDO1/PSMC4/MDH1/EFNA3/PFKP/XYLT2/SDC2/GMPPA/KDELR3/SLC37A4/GUSB/ALDOA/SDHC/DPYSL4/IDH1/ALDH9A1 53
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 50/536 168/3464 1.13542148734735e-06 2.83855371836837e-05 2.33060200034456e-05 P4HA2/ALDOC/PGK1/GAPDH/LDHA/PGM1/TPI1/GBE1/GYS1/ILVBL/GPI/TMEM45A/PPFIA4/AK4/BNIP3L/ENO1/GLRX/SLC2A3/CCNG2/PDK1/AKAP12/FAM162A/P4HA1/PLAC8/PGM2/ANKZF1/XPNPEP1/UGP2/GALK1/CASP6/GCK/HK1/SLC2A1/GCNT2/SCARB1/EFNA3/PFKP/MT1E/SDC2/RBPJ/GRHPR/KDELR3/FBP1/SLC37A4/ALDOA/TPST2/DPYSL4/WSB1/SRPX/PFKL 50
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 55/536 196/3464 2.5498680769622e-06 3.37460781848635e-05 2.77073062991511e-05 UQCRC2/IDH2/LDHA/ECHS1/MAOB/GPI/SLC25A5/ECH1/ATP5F1A/ACAA1/IDH3G/SLC25A11/HADHB/UQCRC1/LDHB/PMPCA/PDHA1/SLC25A4/ATP5MC3/VDAC3/ETFB/NDUFV1/VDAC1/ATP5F1B/MDH2/ATP5F1C/ATP5MC1/PHB2/AIFM1/MRPL11/MDH1/IDH3B/ETFA/MRPL35/FH/NDUFA9/RHOT2/NDUFB6/NDUFAB1/PRDX3/NDUFB2/ATP5MF/UQCR10/SDHB/POLR2F/UQCRQ/SDHC/CYC1/HSD17B10/COX6B1/IDH1/UQCRFS1/TIMM13/NDUFS6/NDUFS3 55
HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM 41/536 131/3464 2.69968625478908e-06 3.37460781848635e-05 2.77073062991511e-05 G0S2/MAOA/LDHA/ECHS1/GCDH/ACAT2/ECH1/ACAA1/IDH3G/AUH/SUCLG2/HADHB/LGALS1/PDHA1/ECI2/NTHL1/BCKDHB/MDH2/PRDX6/SMS/HIBCH/HADH/UROS/ALDH3A2/MDH1/ALAD/IDH3B/HSD17B4/PCBD1/IL4I1/FH/GRHPR/REEP6/ALDOA/SDHC/CRYZ/UROD/HSD17B10/IDH1/ALDH9A1/DHCR24 41
HALLMARK_MTORC1_SIGNALING HALLMARK_MTORC1_SIGNALING 52/536 197/3464 3.269862507768e-05 0.0003269862507768 0.000268472921690426 TUBA4A/PGK1/PLOD2/GAPDH/LDHA/PGM1/HSP90B1/TPI1/TM7SF2/CORO1A/LTA4H/GBE1/GPI/SLA/AK4/ITGB2/PSMD13/CALR/ENO1/GLRX/DHFR/FADS2/SLC2A3/BUB1/PLK1/AURKA/GLA/SLC9A3R1/PDK1/P4HA1/HSPE1/TUBG1/STIP1/ATP5MC1/SLC2A1/MLLT11/HSPD1/SDF2L1/PSMC4/PPA1/PRDX1/CACYBP/SLC37A4/HMBS/CCT6A/ALDOA/IDH1/HSPA4/DHCR24/SORD/EBP/PFKL 52
HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1 50/536 200/3464 0.000209068826378284 0.00174224021981904 0.0014304709173251 PGK1/LDHA/RUVBL2/CDK2/SRSF7/IMPDH2/PRPF31/TUFM/VDAC3/PA2G4/CCT7/HNRNPA2B1/HNRNPA3/CDC20/VDAC1/HNRNPD/CDC45/TCP1/NHP2/SNRPA1/CCT5/HSPE1/PSMB3/CCT4/PHB/NPM1/SNRPA/RANBP1/NME1/PHB2/EXOSC7/HSPD1/MRPL23/PSMC4/CCNA2/PSMD8/SRPK1/PPM1G/PSMD1/HSP90AB1/NDUFAB1/SNRPD2/C1QBP/PRDX3/NCBP1/HNRNPA1/ILF2/CCT2/FBL/CYC1 50
paper_data/RNP_AAV6_D4-AAV6_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 57/278 181/3464 1.74007981997818e-21 8.70039909989092e-20 6.59398668623312e-20 GEM/GADD45B/PPP1R15A/ZC3H12A/GADD45A/CCND1/KLF10/ATF3/PDE4B/SQSTM1/CD44/TNFSF9/INHBA/IL15RA/KLF6/IER3/TNC/JUN/SMAD3/SOD2/PLK2/CDKN1A/FOSB/TSC22D1/IRF1/PHLDA1/MXD1/TUBB2A/ETS2/MYC/PTGS2/DRAM1/CXCL11/NFAT5/CCNL1/NINJ1/TNFAIP3/EIF1/SOCS3/CD83/VEGFA/SPHK1/DUSP4/SPSB1/IFIT2/PMEPA1/DENND5A/NAMPT/SERPINB2/PLAU/TIPARP/PHLDA2/IRS2/ZBTB10/SERPINE1/KDM6B/NFE2L2 57
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 27/278 118/3464 3.10855392066602e-07 7.77138480166505e-06 5.88989163915667e-06 GEM/GADD45B/GADD45A/VIM/IL15/FERMT2/CD44/INHBA/TNC/FAS/JUN/SERPINE2/CXCL8/GLIPR1/CD59/MGP/MYLK/TNFAIP3/NID2/VEGFA/LAMC2/COL7A1/THBS1/ITGA2/PMEPA1/NOTCH2/SERPINE1 27
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 31/278 168/3464 5.93444091163254e-06 9.8907348527209e-05 7.49613588837794e-05 PPP1R15A/STC2/ATF3/DDIT3/NR3C1/KLF6/KLHL24/CAV1/IER3/JUN/TPBG/CDKN1A/PLIN2/BCL2/IDS/MXI1/NEDD4L/TKTL1/HMOX1/PYGM/TNFAIP3/VEGFA/HS3ST1/PIM1/ANXA2/AMPD3/EXT1/TIPARP/KLF7/IRS2/SERPINE1 31
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 33/278 189/3464 1.01155932454315e-05 0.000126444915567893 9.58319360093506e-05 SLAMF7/APOL6/RSAD2/GBP4/IL15/PDE4B/IL15RA/WARS1/FAS/TRIM25/SOD2/EPSTI1/IFIT3/CDKN1A/IRF1/UPP1/PTGS2/CXCL11/STAT1/TNFAIP3/PARP14/SOCS3/NLRC5/PELI1/ARID5B/IFIT2/ZNFX1/PIM1/NAMPT/TRIM21/CSF2RB/MTHFD2/JAK2 33
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 26/278 149/3464 9.50105436447802e-05 0.000840897077346336 0.000637311469146697 IL1R1/IL15/PDE4B/TNFSF9/INHBA/IL15RA/KLF6/RGS1/AHR/TPBG/CCR7/CDKN1A/IRF1/MXD1/CXCL8/MYC/CD70/CXCL11/SLC7A1/P2RX7/SPHK1/AQP9/NAMPT/KIF1B/LAMP3/SERPINE1 26
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 30/278 184/3464 0.00010090764928156 0.000840897077346336 0.000637311469146697 SLC7A11/PPP1R15A/GADD45A/SLC3A2/ATF3/ZMAT3/TNFSF9/DDIT3/TRIB3/IER3/FAS/MDM2/JUN/PLK2/CDKN1A/TSC22D1/MXD1/UPP1/PDGFA/ABHD4/DRAM1/NINJ1/PPM1D/HMOX1/AEN/SPHK1/IRAG2/CDKN2B/PHLDA3/PVT1 30
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 25/278 144/3464 0.000141685508773988 0.00101203934838563 0.000767019295618581 CTH/GADD45B/ANXA1/GADD45A/CCND1/ATF3/LGALS3/LMNA/SQSTM1/CD44/DDIT3/PDCD4/CAV1/IER3/FAS/JUN/BMF/SOD2/CDKN1A/IRF1/FEZ1/HMOX1/CREBBP/PEA15/PMAIP1 25
HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING 13/278 69/3464 0.0027730819796841 0.0173317623730257 0.0131356514827142 IL1R1/CD44/IL15RA/FAS/JUN/IL1R2/IRF1/CXCL11/STAT1/HMOX1/SOCS3/PIM1/CSF2RB 13
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 16/278 96/3464 0.00351549715315262 0.0195305397397368 0.0148020932764321 RSAD2/GBP4/IL15/WARS1/TRIM25/EPSTI1/IFIT3/TENT5A/NUB1/IRF1/CXCL11/PARP14/IFIT2/TRIM21/TMEM140/LAMP3 16
HALLMARK_COAGULATION HALLMARK_COAGULATION 13/278 75/3464 0.00587015107805943 0.0293507553902971 0.0222447830326463 CRIP2/ANXA1/CAPN2/MMP10/THBS1/ITGA2/DUSP14/SERPINB2/CTSO/PLAU/TMPRSS6/KLF7/SERPINE1 13
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 24/278 182/3464 0.00939250292841841 0.0426931951291746 0.0323569478873744 NFKBIZ/GADD45B/GBP4/PLEC/CD44/AHNAK/KLF6/HIPK2/AHR/IL1RL1/GABARAPL1/IL1R2/PLIN2/BCL2/PHLDA1/MXD1/MYC/PRNP/CD83/TTC39B/PIM1/DENND5A/PLAGL1/SOCS2 24
paper_data/RNP_AAV6_D4-RNP_D4-enr-h.all.v7.2.symbols-neg.txt
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paper_data/RNP_AAV6_D4-RNP_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 12/15 200/4231 3.62216114938759e-14 8.33097064359146e-13 7.62560241976335e-13 GADD45A/PLK2/FDXR/SESN1/BAX/CDKN1A/PLXNB2/PHLDA3/MDM2/ATF3/FAS/ZMAT3 12
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 6/15 159/4231 9.68740301849806e-06 0.000111405134712728 0.000101972663352611 GADD45A/FDXR/BAX/CDKN1A/ATF3/FAS 6
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 4/15 200/4231 0.00438275859258634 0.0336011492098286 0.0307562006497287 GADD45A/PLK2/CDKN1A/ATF3 4
paper_data/RNP_AAV6_D4-UT_D4-enr-h.all.v7.2.symbols-neg.txt
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View file @
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1 65/529 200/3554 7.5665712722219e-11 2.7463052142519e-09 2.25486112328051e-09 PGK1/RUVBL2/SRSF7/LDHA/IMPDH2/TUFM/PRPF31/CDK2/PHB2/NPM1/HSPD1/PA2G4/SNRPA/CDC45/VDAC1/SNRPA1/HNRNPA2B1/CCT7/HNRNPD/CCT5/CDC20/NHP2/EXOSC7/PHB/CCT4/PSMC4/TCP1/HNRNPA3/C1QBP/HSPE1/PSMB3/NME1/VDAC3/MRPL23/PPM1G/RANBP1/ILF2/PSMD8/HSP90AB1/CYC1/CCT2/NDUFAB1/FBL/CCT3/SRPK1/CBX3/LSM2/PRDX3/CDK4/HNRNPA1/COX5A/SNRPD3/LSM7/POLD2/SNRPD2/NCBP1/SYNCRIP/RFC4/HPRT1/UBE2E1/SNRPD1/RPL6/HNRNPC/RRP9/PPIA 65
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 64/529 197/3554 1.09852208570076e-10 2.7463052142519e-09 2.25486112328051e-09 UQCRC2/ECHS1/LDHA/SLC25A5/ATP5F1A/ACAA1/SLC25A11/IDH2/GPI/PHB2/HADHB/PMPCA/IDH3G/MDH2/NDUFV1/LDHB/ECH1/VDAC1/ETFB/ATP5MC3/PDHA1/TIMM13/UQCRC1/ATP5MC1/MAOB/ATP5F1B/MRPL11/ATP5F1C/VDAC3/IDH3B/HSD17B10/CYC1/NDUFAB1/TIMM50/TOMM22/RHOT2/SLC25A4/ETFA/MRPS15/UQCRFS1/SDHB/PRDX3/NDUFB2/FXN/COX5A/NDUFA3/NDUFS3/MDH1/AIFM1/ATP5ME/POLR2F/SUCLA2/FH/COX6B1/UQCRQ/ATP5MF/MRPL35/UQCR10/NDUFS6/ATP5PB/NDUFS7/NDUFB7/GRPEL1/NDUFA9 64
HALLMARK_MTORC1_SIGNALING HALLMARK_MTORC1_SIGNALING 53/529 197/3554 4.76346456182618e-06 7.93910760304363e-05 6.5184251898674e-05 TUBA4A/PGK1/LDHA/GAPDH/LTA4H/HSP90B1/TPI1/PGM1/CORO1A/PLOD2/PSMD13/TM7SF2/GPI/HSPD1/GLA/ENO1/SLA/CALR/ITGB2/SDF2L1/GBE1/AK4/PSMC4/PPA1/ATP5MC1/SORD/HSPE1/PLK1/STIP1/CACYBP/GLRX/CCT6A/DHFR/HMBS/SLC2A1/SLC9A3R1/UNG/P4HA1/TUBG1/PDK1/PRDX1/SLC2A3/POLR3G/EBP/MLLT11/UCHL5/FADS2/AURKA/HSPA4/HPRT1/RRP9/PPIA/PSMA3 53
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 46/529 174/3554 3.41755188155415e-05 0.000427193985194268 0.000350748745738452 P4HA2/ALDH7A1/PGK1/FUT8/LDHA/TPI1/GALE/TSTA3/PLOD2/FKBP4/SLC25A13/PPFIA4/SLC25A10/MPI/MDH2/ENO1/GMPPB/GYS1/PGAM1/AK4/PSMC4/KIF20A/FAM162A/GALK1/SLC16A3/PLOD1/SPAG4/NDUFV3/RPE/TALDO1/GLRX/NASP/P4HA1/ANKZF1/HMMR/DPYSL4/MDH1/PGLS/PGM2/TPST1/POLR3K/AURKA/NOL3/IL13RA1/RARS1/PPIA 46
HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM 35/529 131/3554 0.000243083988588841 0.00206981798827082 0.0016994295061592 G0S2/MAOA/ECHS1/LDHA/GCDH/ACAA1/AUH/NTHL1/ACAT2/CD36/HADHB/IDH3G/MDH2/ECH1/SUCLG2/PDHA1/LGALS1/SMS/ALDH3A2/HIBCH/UROS/IDH3B/PRDX6/HSD17B10/ECI2/HADH/PCBD1/MDH1/SUCLA2/GRHPR/FH/UROD/CCDC58/BCKDHB/CRYZ 35
HALLMARK_ALLOGRAFT_REJECTION HALLMARK_ALLOGRAFT_REJECTION 43/529 172/3554 0.000248378158592499 0.00206981798827082 0.0016994295061592 CD40LG/THY1/GZMA/CCR1/PTPRC/IL4/IL9/ZAP70/FASLG/CCND3/PTPN6/LCK/CSK/NPM1/CD4/ITGB2/IL16/SIT1/GCNT1/NME1/IL2RA/HLA-DRA/CCL2/CCL19/PSMB10/CD3D/IL10/IRF8/GZMB/LTB/EIF5A/CCL4/MRPL3/HLA-DMA/CCL5/CD3G/CD40/HLA-DMB/CCL22/RARS1/LIF/EIF4G3/LY86 43
paper_data/RNP_AAV6_D4-UT_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 73/429 185/3554 7.62623935035054e-23 3.81311967517527e-21 2.80966712907651e-21 ATF3/GEM/PLK2/CDKN1A/PPP1R15A/GADD45B/GADD45A/TNFSF9/PDE4B/DRAM1/ZC3H12A/CD44/CCND1/KLF10/SQSTM1/KLF6/IL15RA/ETS2/RNF19B/TUBB2A/TNC/NINJ1/MXD1/IRF1/PHLDA1/TNFAIP3/SOD2/JUN/IER3/CXCL11/DENND5A/INHBA/SMAD3/VEGFA/AREG/SERPINE1/SOCS3/SPSB1/KLF4/IFIT2/DUSP5/SERPINB8/NFAT5/TIPARP/ZBTB10/TNIP1/PTGER4/NFE2L2/EHD1/PLAU/DUSP4/NAMPT/EIF1/ABCA1/DNAJB4/FOSB/MYC/SPHK1/RELA/PTGS2/CD83/IER5/MSC/IL6/PMEPA1/IRS2/BTG1/SAT1/ZFP36/B4GALT1/CXCL10/TANK/TSC22D1 73
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 54/429 186/3554 1.18483453669877e-10 2.96208634174693e-09 2.18258993602406e-09 SLC7A11/ZMAT3/ATF3/PLK2/CDKN1A/FAS/PPP1R15A/GADD45A/DDIT3/MDM2/TNFSF9/DRAM1/TRIB3/PHLDA3/SLC3A2/PLXNB2/RNF19B/PPM1D/ABHD4/SESN1/DDB2/IRAG2/NINJ1/AEN/FDXR/MXD1/XPC/JUN/IER3/PDGFA/ANKRA2/POLH/UPP1/TXNIP/KLF4/BAX/NDRG1/PERP/HMOX1/FOXO3/SPHK1/EPHA2/IER5/PVT1/RRAD/SP1/TM7SF3/BTG1/SAT1/TGFA/TP63/MXD4/TSC22D1/CDKN2B 54
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 45/429 192/3554 4.50270627526548e-06 7.50451045877579e-05 5.52963928541374e-05 SLAMF7/APOL6/CDKN1A/FAS/RSAD2/GBP4/PDE4B/IL15/IFIT3/EPSTI1/WARS1/IL15RA/TRIM25/IRF1/TNFAIP3/SOD2/CXCL11/STAT1/PELI1/UPP1/PARP14/TRIM21/SOCS3/TXNIP/IFIT2/JAK2/NLRC5/CD274/IRF2/ZNFX1/PIM1/RIPK1/NAMPT/CASP7/HERC6/MTHFD2/SAMD9L/ARID5B/PTGS2/IL6/TDRD7/BTG1/HIF1A/CXCL10/IRF5 45
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 35/429 146/3554 3.31168301019497e-05 0.00039652178735444 0.000292173948576956 CTH/ATF3/CDKN1A/FAS/GADD45B/GADD45A/DDIT3/ANXA1/PDCD4/CD44/CCND1/LGALS3/SQSTM1/LMNA/BMF/CAV1/FDXR/IRF1/SOD2/FEZ1/JUN/IER3/TXNIP/BAX/PMAIP1/CREBBP/HMOX1/PEA15/CASP7/RELA/IL6/SAT1/TNFRSF12A/EMP1/IGFBP6 35
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 39/429 171/3554 3.9652178735444e-05 0.00039652178735444 0.000292173948576956 ATF3/CDKN1A/PPP1R15A/STC2/DDIT3/NR3C1/KLHL24/KLF6/PLIN2/CAV1/TPBG/BCL2/IDS/TNFAIP3/JUN/IER3/VEGFA/SERPINE1/TKTL1/PYGM/TES/AMPD3/HS3ST1/NDRG1/ANXA2/TIPARP/NEDD4L/PIM1/HMOX1/CXCR4/VLDLR/MXI1/FOXO3/IL6/IRS2/BTG1/ZFP36/KLF7/EXT1 39
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 34/429 153/3554 0.000216027366851465 0.00156997603358972 0.00115682444580295 IL1R1/CDKN1A/TNFSF9/PDE4B/CCR7/CD70/IL15/KLF6/IL15RA/RGS1/TPBG/MXD1/AHR/IRF1/LAMP3/CXCL11/INHBA/SERPINE1/SLC7A1/BEST1/P2RX7/MET/PTGER4/NAMPT/ABCA1/MYC/SPHK1/RELA/PIK3R5/IL6/GPR132/PROK2/HIF1A/CXCL10 34
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 30/429 129/3554 0.000219796644702561 0.00156997603358972 0.00115682444580295 GEM/FAS/GADD45B/GADD45A/VIM/FERMT2/CD44/IL15/SERPINE2/ACTA2/TNC/TNFAIP3/JUN/INHBA/VEGFA/AREG/CD59/SERPINE1/GLIPR1/THBS1/MGP/NOTCH2/LAMC2/FGF2/FBLN5/IL6/PMEPA1/ITGA2/SAT1/TNFRSF12A 30
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 24/429 97/3554 0.000354490195721972 0.00221556372326232 0.00163252063819329 RSAD2/GBP4/IL15/IFIT3/EPSTI1/WARS1/TENT5A/TRIM25/NUB1/IRF1/LAMP3/CXCL11/PARP14/TRIM21/SAMD9/TXNIP/IFIT2/TMEM140/ELF1/IRF2/HERC6/SAMD9L/TDRD7/CXCL10 24
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 37/429 184/3554 0.00091890504373946 0.00510502802077478 0.0037615995942551 GADD45B/NFKBIZ/GBP4/CD44/PLEC/KLF6/GABARAPL1/AHNAK/PLIN2/HIPK2/MXD1/BCL2/AHR/PHLDA1/IL1R2/DENND5A/IL1RL1/CA2/PRNP/TTC39B/NDRG1/SPRED2/PIM1/PLAGL1/SOCS2/MYC/LRRC8C/TNFRSF8/CD83/SLC1A5/RABGAP1L/EMP1/CXCL10/FAM126B/SNX9/FLT3LG/IKZF4 37
paper_data/RNP_AAV6_D4-UT_electro_D4-enr-h.all.v7.2.symbols-neg.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
paper_data/RNP_AAV6_D4-UT_electro_D4-enr-h.all.v7.2.symbols-pos.txt
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ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 22/35 200/4231 1.90499385053722e-21 6.47697909182654e-20 6.01577005432806e-20 PLK2/CDKN1A/ZMAT3/BAX/FDXR/GADD45A/MDM2/SESN1/ATF3/TNFSF9/PHLDA3/DDB2/FAS/IRAG2/PLXNB2/DRAM1/RPS27L/KRT17/DDIT3/PPM1D/TXNIP/ANKRA2 22
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 8/35 159/4231 3.30280672815503e-05 0.000561477143786355 0.000521495799182373 CDKN1A/BAX/FDXR/GADD45A/ATF3/FAS/DDIT3/TXNIP 8
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 8/35 200/4231 0.00016913791285639 0.00191689634570575 0.00178039908269884 PLK2/CDKN1A/GADD45A/ATF3/TNFSF9/DRAM1/SERPINE1/GEM 8
paper_data/RNP_D4-AAV6_D4-enr-h.all.v7.2.symbols-neg.txt
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bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 95/650 197/3554 3.55937958004268e-23 1.77968979002134e-21 1.53615329243947e-21 IDH2/UQCRC2/ECHS1/BAX/LDHA/MAOB/IDH3G/SLC25A4/SLC25A5/ECH1/ETFB/ATP5MC3/UQCRC1/ATP5F1A/GPI/LDHB/NDUFS7/MDH1/VDAC3/ATP5MC1/UQCRQ/ACAA1/ATP5MF/NDUFB2/SLC25A11/NDUFA3/PHYH/COX6B1/MRPL11/NDUFS6/COX8A/UQCR10/MDH2/NDUFB1/NDUFB6/ATP5ME/ATP5F1C/NDUFA2/HADHB/COX4I1/NDUFAB1/COX7C/NDUFC1/IDH3B/UQCRH/PDHA1/HSD17B10/COX5B/NDUFB8/COX5A/NDUFV1/ATP5PB/UQCRB/FH/NDUFS3/POLR2F/COX7B/VDAC1/ATP5F1B/ATP5PF/NDUFA1/MRPS15/NDUFS8/CYC1/ATP5MG/ETFA/NDUFB7/SDHB/NDUFA4/NDUFB3/ACAA2/NDUFB4/UQCRFS1/NDUFA8/ATP5PD/MRPL35/SDHC/COX7A2/NDUFA9/ATP5PO/SUCLG1/COX6A1/CYB5A/COX17/TOMM22/COX6C/BDH2/NDUFC2/ATP5F1E/TIMM10/NDUFS4/TIMM8B/ATP6V1D/PHB2/PRDX3 95
HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM 47/650 131/3554 8.61319803989667e-07 2.15329950997417e-05 1.85863747176718e-05 ECHS1/ACAT2/G0S2/MAOA/LDHA/ECI2/IDH3G/ECH1/AUH/PRDX6/LGALS1/SUCLG2/MDH1/ACAA1/GCDH/CBR3/HADH/MDH2/UROS/HADHB/IDH3B/PDHA1/HSD17B10/BCKDHB/FH/NTHL1/PCBD1/REEP6/SMS/H2AZ1/ALDH3A2/ACAA2/GRHPR/BLVRA/SDHC/IL4I1/ENO2/UROD/SUCLG1/HSD17B7/HSD17B4/HIBCH/ACOT8/DHCR24/CRYZ/HSDL2/ACADS 47
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 53/650 171/3554 2.6020844679461e-05 0.000433680744657683 0.000374334958546631 P4HA2/ALDOC/BNIP3L/TMEM45A/PLAC8/PGK1/TPI1/GAPDH/PPFIA4/GLRX/CCNG2/PGM1/LDHA/GBE1/KDELR3/GYS1/FAM162A/AK4/GPI/MT1E/ENO1/GALK1/SLC37A4/ILVBL/DPYSL4/CASP6/EFNA3/SDC2/AKAP12/PDK1/CAVIN1/SCARB1/ANKZF1/SLC2A3/XPNPEP1/UGP2/GRHPR/S100A4/PGM2/ENO2/SLC2A1/P4HA1/MT2A/GAA/CDKN1B/STC1/RRAGD/CCN1/HK1/TGM2/RBPJ/NFIL3/WSB1 53
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 53/650 174/3554 4.45025166235006e-05 0.000556281457793757 0.000480158731990401 P4HA2/PGK1/TPI1/PPFIA4/GLRX/PLOD2/LDHA/ALDH7A1/KDELR3/SLC16A3/GMPPB/BIK/GYS1/FAM162A/AK4/FUT8/PGAM1/ENO1/MPI/SLC25A10/GALK1/SLC37A4/MDH1/DPYSL4/SPAG4/CASP6/GALE/EFNA3/SDC2/MDH2/IL13RA1/ANKZF1/PSMC4/TALDO1/PLOD1/PPIA/UGP2/SDC1/NASP/KIF20A/SDHC/PGM2/ENO2/GMPPA/CYB5A/P4HA1/STMN1/STC1/RRAGD/SOD1/TSTA3/PKM/SLC25A13 53
HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1 57/650 200/3554 0.000180049969406494 0.00180049969406494 0.00155411552540342 PGK1/CDK2/LDHA/CDC45/SRSF7/MRPL23/PSMB3/RUVBL2/TYMS/HNRNPD/VDAC3/NHP2/PSMD8/NME1/SNRPD2/AP3S1/RPS5/RANBP1/PRPF31/IMPDH2/NDUFAB1/SNRPA1/HSPE1/HNRNPA1/PSMC4/COX5A/LSM7/PPIA/PCNA/TUFM/PA2G4/VDAC1/SNRPG/PSMB2/CYC1/HNRNPA3/HNRNPA2B1/H2AZ1/LSM2/SNRPA/FBL/RPS3/PHB/RFC4/RPL18/DUT/NPM1/TXNL4A/HPRT1/SNRPB2/EXOSC7/RPL6/PHB2/PRDX3/CCT7/RPL34/SSBP1 57
HALLMARK_DNA_REPAIR HALLMARK_DNA_REPAIR 43/650 145/3554 0.000452501136765981 0.00377084280638317 0.00325483273814127 NME4/RFC5/ADA/GSDME/MPG/POLR2I/GUK1/RFC2/TYMS/NELFE/ZWINT/SDCBP/POLB/NME1/POLR2H/ZNRD1/BCAP31/IMPDH2/USP11/NME3/RPA3/POLR2G/POLR2J/PCNA/EDF1/POLR2F/NUDT21/MRPL40/APRT/NT5C/RFC4/GTF2H5/POLR2E/COX17/DUT/SNAPC5/POLD4/PDE6G/DAD1/HPRT1/RBX1/LIG1/POLA2 43
HALLMARK_ADIPOGENESIS HALLMARK_ADIPOGENESIS 46/650 177/3554 0.00576741678064564 0.0411958341474689 0.0355585094746573 ECHS1/UCP2/CCNG2/TST/PGM1/IDH3G/CAT/GBE1/ECH1/ETFB/UQCRC1/SLC25A10/CMBL/UQCRQ/PHYH/COX8A/HADH/UQCR10/SAMM50/MDH2/EPHX2/CAVIN1/NDUFAB1/ESYT1/SCARB1/CHCHD10/TALDO1/COQ3/NDUFS3/COX7B/REEP6/CYC1/NDUFB7/SDHB/ACAA2/COQ9/CDKN2C/SDHC/ATP5PO/SUCLG1/COX6A1/HIBCH/PEMT/SOD1/PRDX3/ACADS 46
paper_data/RNP_D4-AAV6_D4-enr-h.all.v7.2.symbols-pos.txt
0 → 100644
View file @
bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 39/242 185/3554 4.68411484748802e-11 2.34205742374401e-09 1.82433946691639e-09 ZC3H12A/PPP1R15A/GEM/GADD45B/MYC/CD44/INHBA/KLF10/SQSTM1/PDE4B/IL15RA/KLF6/ETS2/TSC22D1/CCNL1/SERPINB2/DENND5A/IFIT2/NFAT5/PTGS2/CCND1/DUSP4/TUBB2A/CXCL11/KDM6B/SMAD3/CD83/NAMPT/PHLDA1/SOD2/MXD1/JUN/IRF1/FOSB/IER3/TNC/SOCS3/RIPK2/SPHK1 39
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 32/242 192/3554 1.08698210659666e-06 2.71745526649165e-05 2.1167546286356e-05 SLAMF7/APOL6/GBP4/RSAD2/WARS1/PDE4B/IL15RA/CSF2RB/IL15/IFIT2/IFIT3/PTGS2/CXCL11/EPSTI1/TRIM25/JAK2/STAT1/PIM1/NAMPT/SOD2/ZNFX1/IRF1/PELI1/UPP1/PARP14/CD274/NLRC5/SOCS3/RIPK2/IRF9/SPPL2A/ARID5B 32
HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING 15/242 72/3554 7.00975873040559e-05 0.00108116783731711 0.000842172841699647 IL1R1/CD44/IL15RA/CSF2RB/CXCL11/IL1R2/STAT1/HMOX1/PIM1/JUN/IRF1/IL18R1/LEPR/SOCS3/IRF9 15
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 27/242 184/3554 8.64934269853692e-05 0.00108116783731711 0.000842172841699647 NFKBIZ/GBP4/IL1RL1/GADD45B/MYC/CD44/HIPK2/AHNAK/PLEC/KLF6/AHR/DENND5A/GABARAPL1/IL1R2/GATA1/CD83/PIM1/PLIN2/PHLDA1/MXD1/PRNP/BCL2/IL18R1/PLAGL1/TNFRSF8/CDCP1/LRRC8C 27
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 23/242 153/3554 0.000205697742321378 0.00205697742321378 0.00160227715071389 IL1R1/MYC/INHBA/CXCL8/PDE4B/IL15RA/KLF6/IL15/AHR/AQP9/RGS1/P2RX7/CXCL11/TPBG/PTAFR/NAMPT/SLC7A1/MXD1/IRF1/IL18R1/RIPK2/CCR7/SPHK1 23
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 20/242 129/3554 0.000356118458708471 0.00296765382257059 0.00231164613547604 GEM/GADD45B/VIM/CD44/INHBA/CXCL8/THBS1/FERMT2/IL15/MGP/LAMC2/JUN/MYLK/SERPINE2/CD59/TNC/GLIPR1/ECM2/ITGA2/NID2 20
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 20/242 146/3554 0.00178224576999965 0.0127303269285689 0.00991625466014841 CTH/ANXA1/GADD45B/CD44/LMNA/PDCD4/SQSTM1/LGALS3/CAV1/BMF/CCND1/FEZ1/HMOX1/SOD2/CLU/JUN/IRF1/DDIT3/IER3/SLC20A1 20
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 21/242 171/3554 0.00529843489095853 0.029791124430204 0.0232057179772115 STC2/PPP1R15A/KLF6/NR3C1/KLHL24/CAV1/TPBG/IDS/MXI1/HMOX1/PIM1/PLIN2/JUN/EXT1/ANXA2/DDIT3/IER3/BCL2/NEDD4L/LARGE1/AMPD3 21
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 14/242 97/3554 0.00536240239743671 0.029791124430204 0.0232057179772115 GBP4/RSAD2/WARS1/IL15/NUB1/IFIT2/IFIT3/CXCL11/EPSTI1/TRIM25/IRF1/PARP14/RIPK2/IRF9 14
paper_data/RNP_D4-UT_D4-enr-h.all.v7.2.symbols-neg.txt
0 → 100644
View file @
bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 100/613 195/3356 2.66736050848256e-27 1.33368025424128e-25 1.151176640503e-25 UQCRC2/IDH2/ECHS1/SLC25A5/LDHA/IDH3G/ETFB/ATP5F1A/ATP5MC3/SLC25A4/ECH1/SLC25A11/LDHB/ATP5MC1/MDH2/NDUFS7/MRPL11/ACAA1/NDUFA3/HSD17B10/UQCRC1/MAOB/NDUFB2/UQCRQ/NDUFV1/NDUFAB1/MRPS15/GPI/CYC1/ATP5ME/ATP5MF/COX6B1/HADHB/NDUFS6/PHB2/COX8A/ATP5F1C/IDH3B/MDH1/VDAC1/VDAC3/COX5A/TOMM22/UQCR10/NDUFB7/UQCRFS1/COX4I1/NDUFS8/SDHB/NDUFS3/ATP5PB/NDUFC1/PDHA1/TIMM13/UQCRH/COX7C/NDUFB1/NDUFA2/UQCRB/POLR2F/COX5B/NDUFB8/ETFA/ATP5PF/NDUFA4/ATP5F1B/NDUFB6/NDUFB3/TIMM50/FH/ATP6V0B/ATP5MG/NDUFB4/PHYH/CYB5A/NDUFA1/COX7B/MRPL34/TIMM10/COX17/NDUFA8/ATP5PO/ATP5F1E/SUCLG1/PRDX3/ATP5PD/TIMM8B/MRPS11/MRPL35/COX7A2/COX6C/SDHC/PMPCA/NDUFA9/NDUFS4/COX6A1/UQCR11/ATP5MC2/NDUFC2/MRPS12 100
HALLMARK_MYC_TARGETS_V1 HALLMARK_MYC_TARGETS_V1 70/613 200/3356 4.35002456952361e-09 1.0875061423809e-07 9.38689512370884e-08 CDC45/PGK1/LDHA/SRSF7/CDK2/RUVBL2/MRPL23/PSMB3/HNRNPD/IMPDH2/NHP2/SNRPA/SNRPA1/TUFM/PRPF31/PSMC4/NME1/PSMD8/NDUFAB1/RPS5/CYC1/NPM1/LSM7/PA2G4/PHB2/VDAC1/VDAC3/COX5A/RANBP1/FBL/LSM2/SNRPD2/HNRNPA1/TXNL4A/RFC4/HNRNPA2B1/HSPE1/PHB/DUT/RPS3/EXOSC7/AP3S1/PPIA/RPL18/HNRNPA3/HPRT1/PSMB2/SNRPG/RPL6/C1QBP/HSPD1/H2AZ1/CCT7/EEF1B2/SSBP1/PRDX3/PSMA7/RPL34/ILF2/SNRPB2/SNRPD1/RPL14/CCT2/RPL22/HDDC2/TYMS/PPM1G/UBE2L3/CDK4/POLD2 70
HALLMARK_GLYCOLYSIS HALLMARK_GLYCOLYSIS 49/613 169/3356 0.000314287295896915 0.00523812159828192 0.0045213260111486 P4HA2/PPFIA4/TPI1/ALDH7A1/PGK1/LDHA/GLRX/GMPPB/FUT8/FAM162A/MDH2/GALK1/GALE/BIK/PGAM1/DPYSL4/SLC16A3/PLOD2/NASP/PSMC4/KDELR3/MPI/TSTA3/ENO1/SLC25A10/MDH1/NDUFV3/AK4/TALDO1/GYS1/PPIA/EFNA3/CYB5A/SLC25A13/SPAG4/PGLS/ANKZF1/CASP6/POLR3K/FKBP4/SDHC/PLOD1/SLC37A4/SOD1/IL13RA1/NOL3/HOMER1/P4HA1/STC1 49
HALLMARK_DNA_REPAIR HALLMARK_DNA_REPAIR 41/613 143/3356 0.00123719325906828 0.014643993361494 0.0126400784804474 NME4/RFC5/POLR2I/MPG/GUK1/RFC2/IMPDH2/NME3/ZWINT/NME1/POLB/POLR2H/APRT/NELFE/BCAP31/POLR2J/ZNRD1/POLR2G/RFC4/SDCBP/DUT/RPA3/POLR2F/ADA/PRIM1/POLR2E/MRPL40/EDF1/HPRT1/COX17/POLA2/PDE6G/DAD1/SNAPC5/GTF2H5/GTF2A2/NT5C/RBX1/POLD3/TYMS/POLE4 41
HALLMARK_FATTY_ACID_METABOLISM HALLMARK_FATTY_ACID_METABOLISM 38/613 131/3356 0.0014643993361494 0.014643993361494 0.0126400784804474 G0S2/ECHS1/ACAT2/LDHA/AUH/ECI2/MAOA/IDH3G/PRDX6/NTHL1/LGALS1/ECH1/MDH2/ACAA1/HSD17B10/SUCLG2/HADHB/UROS/IDH3B/MDH1/GCDH/SMS/ALDH3A2/PDHA1/HADH/PCBD1/FH/GRHPR/UROD/REEP6/CBR3/H2AZ1/HIBCH/SUCLG1/SDHC/CCDC58/ACOT8/CRYZ 38
HALLMARK_ALLOGRAFT_REJECTION HALLMARK_ALLOGRAFT_REJECTION 45/613 167/3356 0.00289596782213764 0.0241330651844803 0.020830645738183 CD40LG/THY1/GZMA/IL4/PTPRC/SIT1/CCR1/IL9/CCND3/IL16/ZAP70/LCK/LTB/CD3D/FASLG/CD4/HLA-DMA/CCL4/NME1/ITGB2/PTPN6/CCL5/NPM1/RPS9/PSMB10/GZMB/CXCL13/HLA-DRA/HLA-A/CCL19/CD40/LY86/CAPG/IL10/CD247/TRAT1/TGFB1/RPL9/RPL39/IL13/CD3G/HLA-G/CCL2/CSK/LIF 45
HALLMARK_MTORC1_SIGNALING HALLMARK_MTORC1_SIGNALING 50/613 195/3356 0.00522131794472932 0.037295128176638 0.0321915843208875 TUBA4A/TPI1/PGK1/GAPDH/LDHA/TM7SF2/GLRX/SDF2L1/PGM1/LTA4H/PSMD13/CORO1A/DHFR/CALR/GLA/ATP5MC1/HSP90B1/PLOD2/PSMC4/ITGB2/EBP/GPI/ENO1/SLA/GBE1/PPA1/AK4/HSPE1/SEC11A/FADS1/SLC9A3R1/PPIA/HPRT1/FADS2/TUBG1/PRDX1/PDK1/PSMA3/UNG/CACYBP/HSPD1/MLLT11/SLC2A1/SLC37A4/PSMB5/PSMC2/HMBS/SLC2A3/P4HA1/STC1 50
paper_data/RNP_D4-UT_D4-enr-h.all.v7.2.symbols-pos.txt
0 → 100644
View file @
bf0bc939
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
HALLMARK_TNFA_SIGNALING_VIA_NFKB HALLMARK_TNFA_SIGNALING_VIA_NFKB 65/366 177/3356 5.72951694177657e-21 2.86475847088829e-19 1.99025325345923e-19 ZC3H12A/PPP1R15A/CD44/GADD45B/GEM/PDE4B/ETS2/KLF10/ATF3/SQSTM1/DENND5A/KLF6/IL15RA/MYC/TUBB2A/IFIT2/RNF19B/CXCL11/CDKN1A/CCND1/PLK2/INHBA/TNFSF9/MXD1/TNFAIP3/PHLDA1/NFAT5/DUSP4/IRF1/DRAM1/NAMPT/SERPINB2/SERPINB8/SOD2/SOCS3/GADD45A/PTGER4/CD83/DNAJB4/TNC/NFE2L2/KDM6B/VEGFA/SERPINE1/JUN/PTGS2/NFKB1/SMAD3/TRAF1/ATP2B1/EHD1/DUSP5/CCNL1/IL6/CXCL10/IER3/TSC22D1/PLAU/ABCA1/TIPARP/SPHK1/RELA/SPSB1/ZBTB10/NINJ1 65
HALLMARK_INTERFERON_GAMMA_RESPONSE HALLMARK_INTERFERON_GAMMA_RESPONSE 44/366 186/3356 2.36531056210801e-07 5.91327640527003e-06 4.10817097629287e-06 SLAMF7/GBP4/APOL6/RSAD2/WARS1/PDE4B/IFIT3/IL15RA/FAS/EPSTI1/IL15/IFIT2/CXCL11/TRIM25/CDKN1A/STAT1/JAK2/PELI1/CD274/TNFAIP3/PIM1/IRF1/PARP14/NAMPT/ZNFX1/SOD2/SOCS3/CASP7/UPP1/NLRC5/TRIM21/PTGS2/TDRD7/NFKB1/HIF1A/HERC6/IL6/CXCL10/RIPK1/MTHFD2/IL7/SPPL2A/IRF2/ARID5B 44
HALLMARK_INFLAMMATORY_RESPONSE HALLMARK_INFLAMMATORY_RESPONSE 36/366 144/3356 7.81926913117176e-07 1.30321152186196e-05 9.05389057293573e-06 IL1R1/PDE4B/KLF6/CCR7/IL15RA/MYC/IL15/CXCL11/CDKN1A/AHR/INHBA/P2RX7/TNFSF9/MXD1/RGS1/TPBG/IRF1/CXCL8/NAMPT/IL18R1/SLC7A1/AQP9/MET/PTGER4/SERPINE1/NFKB1/HIF1A/ATP2B1/CD70/IL6/CXCL10/ABCA1/GPR132/SPHK1/RELA/PIK3R5 36
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 25/366 108/3356 0.00015982146195944 0.00179644450344473 0.00124805618134055 VIM/CD44/GADD45B/GEM/FERMT2/THBS1/FAS/IL15/SERPINE2/INHBA/TNFAIP3/MGP/CXCL8/LAMC2/CD59/GADD45A/TNC/VEGFA/SERPINE1/JUN/GLIPR1/IL6/NOTCH2/ACTA2/ITGA2 25
HALLMARK_IL2_STAT5_SIGNALING HALLMARK_IL2_STAT5_SIGNALING 36/366 181/3356 0.000179644450344473 0.00179644450344473 0.00124805618134055 NFKBIZ/GBP4/CD44/GADD45B/IL1RL1/HIPK2/PLEC/DENND5A/KLF6/AHNAK/MYC/GABARAPL1/PLIN2/AHR/MXD1/PHLDA1/PRNP/PIM1/IL1R2/BCL2/TNFRSF8/IL18R1/PLAGL1/TTC39B/CD83/LRRC8C/TRAF1/EMP1/RABGAP1L/SPRED2/CXCL10/SLC1A5/NDRG1/FAM126B/IKZF4/FLT3LG 36
HALLMARK_HYPOXIA HALLMARK_HYPOXIA 32/366 160/3356 0.000374219765189437 0.00310025602654461 0.00215386208159942 STC2/PPP1R15A/NR3C1/ATF3/KLHL24/KLF6/DDIT3/IDS/CDKN1A/PLIN2/CAV1/TPBG/TNFAIP3/PIM1/BCL2/ANXA2/AMPD3/HMOX1/VEGFA/SERPINE1/JUN/MXI1/HS3ST1/EXT1/NEDD4L/IL6/VLDLR/IER3/FOXO3/TIPARP/NDRG1/TES 32
HALLMARK_APOPTOSIS HALLMARK_APOPTOSIS 29/366 141/3356 0.000434035843716246 0.00310025602654461 0.00215386208159942 CTH/ANXA1/CD44/GADD45B/PDCD4/ATF3/LMNA/SQSTM1/DDIT3/FAS/LGALS3/FEZ1/BMF/CDKN1A/CCND1/CAV1/IRF1/CDC25B/HMOX1/SOD2/GADD45A/CASP7/JUN/EMP1/IL6/IER3/SLC20A1/CREBBP/RELA 29
HALLMARK_IL6_JAK_STAT3_SIGNALING HALLMARK_IL6_JAK_STAT3_SIGNALING 17/366 68/3356 0.000712568924777292 0.00445355577985807 0.00309404927863824 IL1R1/CD44/IL15RA/FAS/CXCL11/STAT1/PIM1/IRF1/IL1R2/IL18R1/HMOX1/SOCS3/JUN/IL6/CXCL10/IL7/PIK3R5 17
HALLMARK_INTERFERON_ALPHA_RESPONSE HALLMARK_INTERFERON_ALPHA_RESPONSE 21/366 95/3356 0.00102407958828357 0.00568933104601986 0.00395258788460327 GBP4/RSAD2/WARS1/IFIT3/NUB1/EPSTI1/IL15/IFIT2/CXCL11/TRIM25/IRF1/PARP14/SAMD9/TRIM21/TDRD7/ELF1/TMEM140/HERC6/CXCL10/IL7/IRF2 21
HALLMARK_P53_PATHWAY HALLMARK_P53_PATHWAY 33/366 182/3356 0.001842778770276 0.00921389385137998 0.00640123151780083 SLC7A11/PPP1R15A/SLC3A2/ZMAT3/TRIB3/ATF3/DDIT3/FAS/RNF19B/CDKN1A/PDGFA/PLK2/ABHD4/TNFSF9/MXD1/DRAM1/AEN/HMOX1/GADD45A/MDM2/UPP1/JUN/PPM1D/CDKN2B/IER3/FOXO3/TSC22D1/NDRG1/XPC/SPHK1/PRKAB1/NINJ1/OSGIN1 33
HALLMARK_UV_RESPONSE_DN HALLMARK_UV_RESPONSE_DN 21/366 106/3356 0.00428005874314419 0.0194548124688372 0.0135159749783501 INSIG1/NR3C1/ATXN1/MYC/MAP1B/NR1D2/APBB2/CAV1/ANXA2/SLC7A1/MET/SERPINE1/NFKB1/SMAD3/NIPBL/ATP2B1/VLDLR/NOTCH2/CDK13/CDC42BPA/PTEN 21
HALLMARK_COAGULATION HALLMARK_COAGULATION 15/366 68/3356 0.00536754952279412 0.0223647896783089 0.0155376433554567 CRIP2/ANXA1/CAPN2/THBS1/MMP10/CTSO/DPP4/SERPINB2/GNG12/SERPINE1/F8/DUSP6/TMPRSS6/PLAU/ITGA2 15
HALLMARK_COMPLEMENT HALLMARK_COMPLEMENT 26/366 149/3356 0.00923463753505241 0.0341768721299911 0.0237439322166254 ANXA5/LGALS3/ERAP2/JAK2/CTSO/DPP4/TNFAIP3/PIM1/IRF1/SERPINB2/CD59/CASP7/SERPINE1/F8/DUSP6/EHD1/TMPRSS6/DUSP5/PDP1/IL6/VCPIP1/APOBEC3F/RBSN/IRF2/HSPA1A/PIK3R5 26
HALLMARK_HEDGEHOG_SIGNALING HALLMARK_HEDGEHOG_SIGNALING 6/366 18/3356 0.00956952419639752 0.0341768721299911 0.0237439322166254 ETS2/ADGRG1/CDK6/VEGFA/VLDLR/TLE3 6
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